Immune Reconstitution in Late-Presenting HIV-Positive a Case with Idiopathic Liver Cirrhosis and Ischemic Brain Stroke

Summary A patient diagnosed with late-presenting HIV infection [CD4 count 86 cells/mm 3 , viral load (VL) 95 000 copies RNA/mL], treated DRV/c 800/150 mg (Rezolsta®) and TDF/FTC 200/245 mg, was hospitalized ischemic brain stroke, confirmed by CT scan MRI. Motor functions quickly recovered, but nausea, abdominal heaviness, ascites, hepatosplenomegaly appeared. Laboratory investigations revealed anaemia, thrombocytopenia, normal transaminases, increased GGT negative serological tests for HBV HCV she Gastroenterologists liver cirrhosis. After 20 days of hospital treatment, the recovered from stroke ascites persisting anaemia thrombocytopenia. Liver cirrhosis had been confirmed, relevant treatment administered. Six months later, an MRI improved image. Follow-up showed stabilized somatic neurologic status, laboratory parameters, stable T-helper undetectable (VL). ART regimen continued Raltegravir 400 (Isentress®) 2×1 tablet/24 h, 1 h. Three her abroad. The access to precise diagnosis adherence has transformed HIV-infection into a manageable chronic health condition, even in complicated cases.